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CDK12-IN-7

CAT: 0804-HY-162528Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162528Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK12-IN-7 (Compound 2) is a CDK12 and CDK2 inhibitor with IC50 values ​​of 42 and 196 nM, respectively. CDK12-IN-7 has anti-cell proliferation activity and can be used in cancer research[1].
CAS Number
3033863-94-1
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk12-in-7.html
Smiles
O=C(NCC1=CC=CC=C1)N(C2=CC=C(N(C=CC(N3C)=O)C3=N4)C4=N2)[C@H](CC5)CC[C@@H]5NC6=NC(OC7COC7)=C(C(F)(F)F)C=N6
Molecular Formula
C32H32F3N9O4
Molecular Weight
663.65
References & Citations
[1]Hu pu, et al. Tricyclic derivative, pharmaceutical composition and use.WO2024066984A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK12; CDK2

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