U-104489

• Description :

  U-104489 is a HIV-1 inhibitor with the Ki values of 0.13, 0.12 and > 100 μM aganist HIV-1 RT p66/p51 wild type (G190), G190A and G190E, respectively[1].

• UNSPSC :

  12352005

• Target :

  HIV

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/u-104489.html

• Smiles :

  O=C(N1CCC(CC1)N(CC)C2=NC=CC=C2NC(C)(C)C)C3=CC4=C(N3)C=CC(NS(=O)(C)=O)=C4

• Molecular Formula :

  C26H36N6O3S

• Molecular Weight :

  512.67

• References & Citations :

  [1]Fan N, et al. A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation. Biochemistry. 1996;35 (30) :9737-9745.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [177577-60-5]