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U-104489

CAT: 0804-HY-117556Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-117556Size:1 Each
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Description
U-104489 is a HIV-1 inhibitor with the Ki values of 0.13, 0.12 and > 100 μM aganist HIV-1 RT p66/p51 wild type (G190), G190A and G190E, respectively[1].
CAS Number
177577-60-5
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/u-104489.html
Smiles
O=C(N1CCC(CC1)N(CC)C2=NC=CC=C2NC(C)(C)C)C3=CC4=C(N3)C=CC(NS(=O)(C)=O)=C4
Molecular Formula
C26H36N6O3S
Molecular Weight
512.67
References & Citations
[1]Fan N, et al. A drug resistance mutation in the inhibitor binding pocket of human immunodeficiency virus type 1 reverse transcriptase impairs DNA synthesis and RNA degradation. Biochemistry. 1996;35 (30) :9737-9745.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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