U-54494A

CAT: 0804-HY-100963Size: 1 EachDry Ice: NoHazardous: No

CAT#:0804-HY-100963Size:1 Each

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Description

U-54494A is a benzamide derivative related to κ-opioid receptor agonists, U-54494A has an anticonvulsant activity[1].

CAS Number

[112465-94-8]

UNSPSC

12352005

Target

Opioid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/u-54494a.html

Solubility

10 mM in DMSO

Smiles

ClC1=CC=C(C(N([C@@H]2[C@H](N3CCCC3)CCCC2)C)=O)C=C1Cl.Cl

Molecular Formula

C18H25Cl3N2O

Molecular Weight

391.76

References & Citations

[1]Fischer, et, al. Anticonvulsant and related effects of U-54494A in various seizure tests. J Pharmacol Exp Ther. 1993, 267, 1.|[2]G De Sarro, et, al. Anticonvulsant effects of U-54494A and U-50488H in genetically epilepsy-prone rats and DBA/2 mice: a possible involvement of glycine/NMDA receptor complex. Gen Pharmacol. 1993, 24, 2.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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Catalog	Name
468413	U-54494A Hydrochloride
256999-01	U-54494A hydrochloride discontinued
463138-01	Protected U-U 5’-CEP
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N2171-81H	Neuromedin U (Neuromedin-U, NmU)
TBI1582-5MG	U-73343, U-73122 negative control
AP79194-01	Neuromedin-U
sc-3574A	U-73122
M31964-01	Gomisin U
ARC0966	U-138MG

U-54494A

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