U-54494A

• Description:

  U-54494A is a benzamide derivative related to κ-opioid receptor agonists, U-54494A has an anticonvulsant activity[1].

• UNSPSC:

  12352005

• Target:

  Opioid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/u-54494a.html

• Solubility:

  10 mM in DMSO

• Smiles:

  ClC1=CC=C (C (N ([C@@H]2[C@H] (N3CCCC3) CCCC2) C) =O) C=C1Cl.Cl

• Molecular Formula:

  C18H25Cl3N2O

• Molecular Weight:

  391.76

• References & Citations:

  [1]Fischer, et, al. Anticonvulsant and related effects of U-54494A in various seizure tests. J Pharmacol Exp Ther. 1993, 267, 1.|[2]G De Sarro, et, al. Anticonvulsant effects of U-54494A and U-50488H in genetically epilepsy-prone rats and DBA/2 mice: a possible involvement of glycine/NMDA receptor complex. Gen Pharmacol. 1993, 24, 2.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  112465-94-8