U-54494A

• Description :

  U-54494A is a benzamide derivative related to κ-opioid receptor agonists, U-54494A has an anticonvulsant activity[1].

• UNSPSC :

  12352005

• Target :

  Opioid Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/u-54494a.html

• Solubility :

  10 mM in DMSO

• Smiles :

  ClC1=CC=C(C(N([C@@H]2[C@H](N3CCCC3)CCCC2)C)=O)C=C1Cl.Cl

• Molecular Formula :

  C18H25Cl3N2O

• Molecular Weight :

  391.76

• References & Citations :

  [1]Fischer, et, al. Anticonvulsant and related effects of U-54494A in various seizure tests. J Pharmacol Exp Ther. 1993, 267, 1.|[2]G De Sarro, et, al. Anticonvulsant effects of U-54494A and U-50488H in genetically epilepsy-prone rats and DBA/2 mice: a possible involvement of glycine/NMDA receptor complex. Gen Pharmacol. 1993, 24, 2.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [112465-94-8]