U-80125

• Description :

  U80215, a dansylated peptide, is a competitive human renin inhibitor with the IC50 of 2.3 μM. U80215 shows excitation and emission maxima at 340 and 530 nm[1].

• UNSPSC :

  12352100

• Target :

  Renin

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Cardiovascular Disease

• Smiles :

  O=C([C@H]([C@H](CC)C)NC([C@H](C(C)C)CC([C@H](CC(C)C)NC([C@H](CC1=CN=CN1)NS(=O)(C2=CC=CC3=C(N(C)C)C=CC=C32)=O)=O)O)=O)NCC4=NC=CC=C4

• Molecular Formula :

  C42H60N8O6S

• Molecular Weight :

  805.04

• References & Citations :

  [1]Epps DE, et al. An experimental method for the determination of enzyme-competitive inhibitor dissociation constants from displacement curves: application to human renin using fluorescence energy transfer to a synthetic dansylated inhibitor peptide. Anal Biochem. 1989 Aug 15;181 (1) :172-81.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [123300-09-4]