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U-96988

CAT: 0804-HY-19215Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-19215Size:1 Each
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Description
U-96988 (PNU-96988) is a non-peptide HIV-1 protease inhibitor with a Ki value of 38 nM. U-96988 is also effective against HIV-2 protease. U-96988 exhibits an IC50 for HIV-1IIIB of 5 μM. U-96988 can be used for research on HIV infection[1][2].
CAS Number
149394-65-0
Product Name Alternative
PNU-96988
UNSPSC
12352005
Target
HIV; HIV Protease
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
O=C1C(C(C2=CC=CC=C2)CC)=C(O)C=C(C(CC3=CC=CC=C3)CC)O1
Molecular Formula
C24H26O3
Molecular Weight
362.46
References & Citations
[1]Koeplinger KA, et al. Equilibrium distribution of HIV antiviral drugs into human peripheral blood mononuclear cells (PBMC) is controlled by free drug concentration in the extracellular medium. J Pharm Biomed Anal. 1999 Mar;19 (3-4) :399-411.|[2]Thaisrivongs S, et al. Structure-based design of HIV protease inhibitors: 5,6-dihydro-4-hydroxy-2-pyrones as effective, nonpeptidic inhibitors. J Med Chem. 1996 Nov 8;39 (23) :4630-42.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1

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