(+)-U-50488

• UNSPSC Description:

  (+)-U-50488 ((+)-Trans-(1R,2R)-U-50488) is a less active κ opioid receptor (KOR) agonist than the enantiomer of (-)-Trans-(1S,2S)-U-50488 (HY-15997)[1].

• Target Antigen:

  Opioid Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/plus-u-50488.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N(C)[C@H]1[C@H](N2CCCC2)CCCC1)CC3=CC=C(Cl)C(Cl)=C3

• Molecular Weight:

  369.33

• References & Citations:

  [1]DeCosta B, et al. Synthesis and absolute configuration of optically pure enantiomers of a kappa-opioid receptor selective agonist. FEBS Lett. 1987;223(2):335-339.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  67198-17-8