ROCK2-IN-9

ROCK2-IN-9

• UNSPSC Description: ROCK2-IN-9 (compound 7u) is a selective ROCK2 inhibitor (IC50=36.8 nM) with anticancer activity. ROCK2-IN-9 inhibits cancer cell migration and invasion by regulating multiple cellular activities of the actin cytoskeleton. ROCK2-IN-9 can be used in breast cancer research[1].
• Target Antigen: ROCK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Cytoskeleton;Stem Cell/Wnt;TGF-beta/Smad
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/rock2-in-9.html
• Smiles: CC(C=C1)=CC=C1CN(CC2)CCN2C3=NC4=C(C(OCC)=O)C=NN4C(NC5=CC=C(NN=C6)C6=C5)=C3
• Molecular Weight: 510.59
• References & Citations: [1]Zhi Cao, et al. "Discovery of novel pyrazolo [1, 5-a] pyrimidine derivatives as selective ROCK2 inhibitors with anti-breast cancer migration and invasion activities." Bioorganic Chemistry (2024): 107675.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported