PHD2-IN-2

CAT: 0804-HY-162438Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-162438Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PHD2-IN-2 (Compound 12) is a PHD2 inhibitor, with an IC50 of 34.3 nM. PHD2-IN-2 has high erythropoietin (EPO) inducing activity, with an EC50 of 6.79 μM. PHD2-IN-2 can be used for the research of anemia, ischemia, and hypoxia[1].
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/phd2-in-2.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C(NCC(O)=O)=O)C2=NC=NN2C(C(CC3)CC4=C3C=CC=C4)=C1
Molecular Formula
C19H18N4O4
Molecular Weight
366.37
References & Citations
[1]Tang HT, et al. Prolyl hydroxylase inhibitor and use thereof. WO2024061172A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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