PHD2-IN-2

• UNSPSC Description:

  PHD2-IN-2 (Compound 12) is a PHD2 inhibitor, with an IC50 of 34.3 nM. PHD2-IN-2 has high erythropoietin (EPO) inducing activity, with an EC50 of 6.79 μM. PHD2-IN-2 can be used for the research of anemia, ischemia, and hypoxia[1].

• Target Antigen:

  HIF/HIF Prolyl-Hydroxylase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/phd2-in-2.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC1=C(C(NCC(O)=O)=O)C2=NC=NN2C(C(CC3)CC4=C3C=CC=C4)=C1

• Molecular Weight:

  366.37

• References & Citations:

  [1]Tang HT, et al. Prolyl hydroxylase inhibitor and use thereof. WO2024061172A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported