PHD2-IN-2

PHD2-IN-2

• UNSPSC Description: PHD2-IN-2 (Compound 12) is a PHD2 inhibitor, with an IC50 of 34.3 nM. PHD2-IN-2 has high erythropoietin (EPO) inducing activity, with an EC50 of 6.79 μM. PHD2-IN-2 can be used for the research of anemia, ischemia, and hypoxia[1].
• Target Antigen: HIF/HIF Prolyl-Hydroxylase
• Type: Reference compound
• Related Pathways: Metabolic Enzyme/Protease
• Applications: Metabolism-sugar/lipid metabolism
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/phd2-in-2.html
• Solubility: 10 mM in DMSO
• Smiles: OC1=C(C(NCC(O)=O)=O)C2=NC=NN2C(C(CC3)CC4=C3C=CC=C4)=C1
• Molecular Weight: 366.37
• References & Citations: [1]Tang HT, et al. Prolyl hydroxylase inhibitor and use thereof. WO2024061172A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported