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HIF-PHD-IN-2

CAT: 0804-HY-139993Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-139993Size:1 Each
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Description
HIF-PHD-IN-2 (compound 25) is a potent PHD inhibitor with IC50s of [1].
CAS Number
2711720-45-3
UNSPSC
12352005
Target
HIF/HIF Prolyl-Hydroxylase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/hif-phd-in-2.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C=NN1C2=NC=C(NS(=O)(CC)=O)C=C2)C3=CC=C(C#N)C=C3
Molecular Formula
C17H15N5O3S
Molecular Weight
369.40
References & Citations
[1]Sabnis RW. Novel Compounds as PHD Inhibitors for Treating Heart, Lung, Liver, and Kidney Diseases. ACS Med Chem Lett. 2021;12 (12) :1868-1869. Published 2021 Nov 4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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