PHD2-IN-5

• Description:

  PHD2-IN-5 (compound 22) is a potent PHD2 inhibitor with an IC50 of 0.82 μM. PHD2-IN-5 can be used in the study of renal anemia[1].

• UNSPSC:

  12352005

• Target:

  HIF/HIF Prolyl-Hydroxylase

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Cardiovascular Disease

• Smiles:

  OC1=C (C (NCC (O) =O) =O) C2=NC=NN2C=C1.Cl

• Molecular Formula:

  C9H9ClN4O4

• Molecular Weight:

  272.65

• References & Citations:

  [1]Ogoshi Y, et al. Lead Generation for a HIF Prolyl Hydroxylase Inhibitor: Discovery of (7-Hydroxy-[1, 2, 4] triazolo [1, 5-a] pyridine-8-carbonyl) glycine as a Lead Compound of Enarodustat[J]. ACS Medicinal Chemistry Letters, 2025.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1262131-72-5