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PHD2-IN-6

CAT: 0931-T212392-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T212392-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1193382-79-4
Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Chromatin/Epigenetic|||Metabolism
Bioactivity
PHD2-IN-6 (Example 89) is an inhibitor of HIF prolyl hydroxylase 2 (PHD2) with an IC50 of 31.6 nM. This compound can stimulate the production of the gene encoding erythropoietin (EPO) . PHD2-IN-6 is applicable in research on inflammatory diseases such as inflammatory bowel disease (IBD) and rheumatoid arthritis.
Smiles
O=C(O)C=1C=NN(C1)C2=NC=3C=C(Cl)C(=CC3N2)S(=O)(=O)C=4C=CC=CC4
Molecular Formula
C17H11ClN4O4S
Molecular Weight
402.81
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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