PHD2-IN-6

• Target :

  HIF/HIF Prolyl-Hydroxylase

• Related Pathways :

  Chromatin/Epigenetic|||Metabolism

• Bioactivity :

  PHD2-IN-6 (Example 89) is an inhibitor of HIF prolyl hydroxylase 2 (PHD2) with an IC50 of 31.6 nM. This compound can stimulate the production of the gene encoding erythropoietin (EPO) . PHD2-IN-6 is applicable in research on inflammatory diseases such as inflammatory bowel disease (IBD) and rheumatoid arthritis.

• Smiles :

  O=C(O)C=1C=NN(C1)C2=NC=3C=C(Cl)C(=CC3N2)S(=O)(=O)C=4C=CC=CC4

• Molecular Formula :

  C17H11ClN4O4S

• Molecular Weight :

  402.81

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1193382-79-4