PHD2-IN-6

• Description :

  PHD2-IN-6 (Example 89) is a HIF prolyl hydroxylase 2 (PHD2) inhibitor with an IC50 of 31.6 nM. PHD2-IN-6 stimulates encoding erythropoietin (EPO) production. PHD2-IN-6 can be used for inflammatory diseases like inflammatory bowel disease (IBD) and rheumatoid arthritis research[1].

• UNSPSC :

  12352005

• Target :

  HIF/HIF Prolyl-Hydroxylase

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Inflammation/Immunology

• Smiles :

  O=C(C1=CN(C2=NC3=C(N2)C=C(S(=O)(C4=CC=CC=C4)=O)C(Cl)=C3)N=C1)O

• Molecular Formula :

  C17H11ClN4O4S

• Molecular Weight :

  402.81

• References & Citations :

  [1]Hocutt F M, et al. Benzoimidazoles as prolyl hydroxylase inhibitors. WO2009134750A1. 2009-11-05.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1193382-79-4]