U-89843A

CAT: 0804-HY-129431-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-129431-01Size:1 mg
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Description
U-89843A is a precursor of U-97924 and forms U-97924 as the major metabolite. Although U-97924 showed mutagenic potential in rat hepatocytes in a serum-free in vitro assay, no genotoxicity of U-97924 was observed in rats at high oral doses. Rat serum also inhibited the in vitro metabolism of U-89843 and the formation of the corresponding hydroxylated metabolite, U-97924[1].
CAS Number
[157013-32-6]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/u-89843a-1.html
Smiles
CN1C(C)=CC2=C(N3CCCC3)N=C(N4CCCC4)N=C21
Molecular Formula
C16H23N5
Molecular Weight
285.39
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Zhao Z, et al. Contribution of serum protein association to discrepancy between the in vivo and in vitro UDS results for 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) . Mutat Res. 1997 Dec 12;395 (2-3) :119-26.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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