CDK2-IN-28

CDK2-IN-28

• CAS Number: 3025006-64-5
• UNSPSC Description: CDK2-IN-28 (compound 22) is a CDK2 inhibitor with good selectivity and cellular effects against other CDKs. CDK2-IN-28 has anti-proliferative effects on MKN1 cells (EC50: 0.31 μM)[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cdk2-in-28.html
• Solubility: 10 mM in DMSO
• Smiles: CS(C1=CC=C(CN2)C(OCCCCCN(CC3CNC3)C4=NC5=C(C(C)C)C=NN5C2=N4)=C1)(=O)=O
• Molecular Weight: 513.66
• References & Citations: [1]Niu P, et al. Discovery of novel macrocyclic derivatives as potent and selective cyclin-dependent kinase 2 inhibitors. Bioorg Med Chem. 2024 Apr 15;104:117711.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported