CDK2-IN-4

CAT: 0804-HY-117535-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-117535-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
CDK2-IN-4 (compound 73) is a potent and selective CDK2 inhibitor with an IC50 of 44 nM for CDK2/cyclin A, shows 2,000-fold selectivity over CDK1/cyclin B (IC50=86 uM) [1].
CAS Number
[2079895-42-2]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk2-in-4.html
Purity
99.85
Solubility
DMSO : 20.83 mg/mL (ultrasonic)
Smiles
O=S(C1=CC=C(C=C1)NC2=NC3=NC=NC3=C(C4=CC(C5=CC=CC=C5)=CC=C4)N2)(N)=O
Molecular Formula
C23H18N6O2S
Molecular Weight
442.49
Precautions
H302, H315, H319, H335
References & Citations
[1]Coxon CR, et al. Cyclin-Dependent Kinase (CDK) Inhibitors: Structure-Activity Relationships and Insights into the CDK-2 Selectivity of 6-Substituted 2-Arylaminopurines. J Med Chem. 2017 Mar 9;60 (5) :1746-1767.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK1; CDK2

Related Products

CatalogName
HY-159155CDK2/4-IN-1
HY-169048CDK2/4-IN-2
HY-148214-01CDK2/4/6-IN-2
HY-148213CDK2/4/6-IN-1
HY-179688PROTAC CDK2/4 Degrader-1
HY-P0235CDK2
HY-134622-01GSK-3/CDK5/CDK2-IN-1
HY-159805-01CDK2-IN-31
HY-144811CDK2-IN-9
HY-144810CDK2-IN-8

Alternative Products

CatalogName
C07088-01CDK2-IN-73 (CDK2-IN-4)
BA3788-1CDK2-IN-4
T204856-01CDK2 degrader 4
A18667-1CDK2-IN-4 1mg
A18667-25CDK2-IN-4 25mg
MBS5821390EGFR/CDK2-IN-4
A18667-10CDK2-IN-4 10mg
A18667-50CDK2-IN-4 50mg
T89458-01CDK2/4-IN-1
T200624-01CDK2/4-IN-2

Popular Products