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CDK2-IN-50

CAT: 0804-HY-179231Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-179231Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK2-IN-50 is a CDK2 inhibitor (IC50 = 0.77 nM) . CDK2-IN-50 can induce G1 phase arrest, indicating that it has an effective CDK2/cyclin E targeting mechanism. CDK2-IN-50 also has a significant pro-apoptotic effect. CDK2-IN-50 can be used for the study of breast cancer[1].
UNSPSC
12352005
Target
Apoptosis; CDK
Related Pathways
Apoptosis; Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(NC1=CC=C(C)C=C1)C2=C(N)C3=C(S2)N=C4CCCCCC4=C3C5=CC=C(OC)C=C5
Molecular Formula
C27H27N3O2S
Molecular Weight
457.59
References & Citations
[1]Ibrahim OF, et al. CDK2 inhibitors: rationally directed discovery of a novel potent lead derived from cyclohepta[e]thieno[2,3-b]pyridine. RSC Med Chem. 2025 Jul 24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2

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