CDK2-IN-8

CDK2-IN-8

• CAS Number: 2919216-36-5
• UNSPSC Description: CDK2-IN-8 is a potent CDK2 inhibitor with an IC50 of 1.74 μM. CDK2-IN-8 shows antiproliferative activity. CDK2-IN-8 has the potential for the research of melanoma[1].
• Target Antigen: CDK
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/cdk2-in-8.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(NN1C(COC2=CC=CC=C2)=NC3=C(C=CC=C3)C1=O)CN4CCN(C)CC4
• Molecular Weight: 407.47
• References & Citations: [1]Mohammed ER, et al. Development of newly synthesised quinazolinone-based CDK2 inhibitors with potent efficacy against melanoma. J Enzyme Inhib Med Chem. 2022 Dec;37(1):686-700.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported