CDK2-IN-8

CAT: 0804-HY-144810Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-144810Size:1 Each
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Description
CDK2-IN-8 is a potent CDK2 inhibitor with an IC50 of 1.74 μM. CDK2-IN-8 shows antiproliferative activity. CDK2-IN-8 has the potential for the research of melanoma[1].
CAS Number
[2919216-36-5]
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cdk2-in-8.html
Solubility
10 mM in DMSO
Smiles
O=C(NN1C(COC2=CC=CC=C2)=NC3=C(C=CC=C3)C1=O)CN4CCN(C)CC4
Molecular Formula
C22H25N5O3
Molecular Weight
407.47
References & Citations
[1]Mohammed ER, et al. Development of newly synthesised quinazolinone-based CDK2 inhibitors with potent efficacy against melanoma. J Enzyme Inhib Med Chem. 2022 Dec;37 (1) :686-700.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2

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