Aa1 toxin

• UNSPSC Description:

  Aa1 toxin, a neurotoxic peptide that can be obtained from the venom of Androctonus australis Garzoni, is a specific potassium channel blocker. Aa1 toxin can be used in the study of neurological diseases[1].

• Target Antigen:

  Potassium Channel

• Type:

  Peptides

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/aa1-toxin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C([C@@H](N)CCC(N)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]1CCCCN)=O)=O)C)=O)C)=O)C(C)C)=O)=O)[C@H](CC)C)=O)C(C)C)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N3[C@H](C(O)=O)CCC3)=O)CC4=CC=C(O)C=C4)=O)=O)C(C)C)=O)CO)=O)C)=O)CSSC[C@H](NC5=O)C(N[C@H]2C(C)C)=O)=O)CO)=O)=O)=O)CCC(N)=O)=O)CSSC[C@H](NC1=O)C(N[C@H](C(N[C@H](C(NCC(N[C@H]5CCCNC(N)=N)=O)=O)CC(N)=O)=O)[C@H](CC)C)=O)=O)CCCCN)=O)CCCCN)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CC(N)=O

• Molecular Weight:

  3868.46

• References & Citations:

  [1]Pisciotta M, et al. Fast K(+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom. Biochim Biophys Acta. 2000 Sep 29;1468(1-2):203-12.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported