Aa1 toxin

• Description :

  Aa1 toxin, a neurotoxic peptide that can be obtained from the venom of Androctonus australis Garzoni, is a specific potassium channel blocker. Aa1 toxin can be used in the study of neurological diseases[1].

• UNSPSC :

  12352209

• Target :

  Potassium Channel

• Type :

  Peptides

• Related Pathways :

  Membrane Transporter/Ion Channel

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/aa1-toxin.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C([C@@H](N)CCC(N)=O)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H]1CCCCN)=O)=O)C)=O)C)=O)C(C)C)=O)=O)[C@H](CC)C)=O)C(C)C)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CSSC[C@H](NC2=O)C(N[C@H](C(N3[C@H](C(O)=O)CCC3)=O)CC4=CC=C(O)C=C4)=O)=O)C(C)C)=O)CO)=O)C)=O)CSSC[C@H](NC5=O)C(N[C@H]2C(C)C)=O)=O)CO)=O)=O)=O)CCC(N)=O)=O)CSSC[C@H](NC1=O)C(N[C@H](C(N[C@H](C(NCC(N[C@H]5CCCNC(N)=N)=O)=O)CC(N)=O)=O)[C@H](CC)C)=O)=O)CCCCN)=O)CCCCN)=O)CC(N)=O)=O)[C@@H](C)O)=O)CCC(O)=O)=O)CC(N)=O

• Molecular Formula :

  C156H260N54O49S6

• Molecular Weight :

  3868.46

• References & Citations :

  [1]Pisciotta M, et al. Fast K (+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom. Biochim Biophys Acta. 2000 Sep 29;1468 (1-2) :203-12.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Peptides

• Clinical Information :

  No Development Reported