Aa1 toxin

• Description:

  Aa1 toxin, a neurotoxic peptide that can be obtained from the venom of Androctonus australis Garzoni, is a specific potassium channel blocker. Aa1 toxin can be used in the study of neurological diseases[1].

• UNSPSC:

  12352209

• Target:

  Potassium Channel

• Type:

  Peptides

• Related Pathways:

  Membrane Transporter/Ion Channel

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/aa1-toxin.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C ([C@@H] (N) CCC (N) =O) N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (NCC (NCC (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (N[C@H] (C (NCC (N[C@H] (C (N[C@H] (C (N[C@H] (C (NCC (N[C@H]1CCCCN) =O) =O) C) =O) C) =O) C (C) C) =O) =O) [C@H] (CC) C) =O) C (C) C) =O) CCCNC (N) =N) =O) CCCNC (N) =N) =O) CSSC[C@H] (NC2=O) C (N[C@H] (C (N3[C@H] (C (O) =O) CCC3) =O) CC4=CC=C (O) C=C4) =O) =O) C (C) C) =O) CO) =O) C) =O) CSSC[C@H] (NC5=O) C (N[C@H]2C (C) C) =O) =O) CO) =O) =O) =O) CCC (N) =O) =O) CSSC[C@H] (NC1=O) C (N[C@H] (C (N[C@H] (C (NCC (N[C@H]5CCCNC (N) =N) =O) =O) CC (N) =O) =O) [C@H] (CC) C) =O) =O) CCCCN) =O) CCCCN) =O) CC (N) =O) =O) [C@@H] (C) O) =O) CCC (O) =O) =O) CC (N) =O

• Molecular Formula:

  C156H260N54O49S6

• Molecular Weight:

  3868.46

• References & Citations:

  [1]Pisciotta M, et al. Fast K (+) currents from cerebellum granular cells are completely blocked by a peptide purified from Androctonus australis Garzoni scorpion venom. Biochim Biophys Acta. 2000 Sep 29;1468 (1-2) :203-12.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Peptides

• Clinical Information:

  No Development Reported