Pertussis Toxin
CAT:
804-HY-112779
Size:
50 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Pertussis Toxin
- CAS Number: 70323-44-3
- UNSPSC Description: Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, which causes whooping cough. Pertussis Toxin inhibits G protein-coupled receptor (GPR) signaling through Gi proteins[1][2][3].
- Target Antigen: Others
- Type: Reference compound
- Related Pathways: Others
- Applications: COVID-19-immunoregulation
- Field of Research: Infection
- Assay Protocol: https://www.medchemexpress.com/Pertussis_Toxin.html
- Purity: 99.0
- Solubility: 10 mM in DMSO
- References & Citations: [1]Carbonetti NH, et al. Pertussis toxin and adenylate cyclase toxin: key virulence factors of Bordetella pertussis and cell biology tools. Future Microbiol. 2010 Mar;5(3):455-69.|[2]Petronila Penela, et al. G protein-coupled receptor kinase 2 positively regulates epithelial cell migration. EMBO J. 2008 Apr 23;27(8):1206-18.|[3]Nicholas H Carbonetti, et al. Contribution of pertussis toxin to the pathogenesis of pertussis disease. Pathog Dis. 2015 Nov;73(8):ftv073.
- Shipping Conditions: Isolate blue ice and the product with bubble pack to avoid direct contact
- Storage Conditions: Store at 4°C, do not freeze
- Clinical Information: No Development Reported