HG1 Toxin

HG1 Toxin

• UNSPSC Description: HG1 Toxin is a peptide found in the venom of the scorpion Heterometrus fulvipes, which has the activity of inhibiting potassium channel Kv1.3. HG1 Toxin also has the activity of inhibiting trypsin (Ki=107 nM) and can be used in the study of autoimmune diseases[1].
• Target Antigen: Potassium Channel; Ser/Thr Protease
• Type: Peptides
• Related Pathways: Membrane Transporter/Ion Channel;Metabolic Enzyme/Protease
• Applications: Metabolism-protein/nucleotide metabolism
• Field of Research: Endocrinology; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/hg1-toxin.html
• Smiles: O=C(N[C@@H](CC1=CNC=N1)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C(C)C)C(N[C@@H](CC(N)=O)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCCN)C(N[C@@H](CC4=CC=CC=C4)C(NCC(NCC(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC5=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC(C)C)C(N6[C@@H](CCC6)C(N7[C@@H](CCC7)C(N[C@@H](CCCCN)C(N[C@@H]([C@H](O)C)C(NCC(N8[C@@H](CCC8)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@H]5CCCNC(N)=N)=O)=O)=O)NC9=O)C(N[C@@H](CCCCN)C(NCC(N[C@@H](CO)C(N[C@@H](CC%10=CC=CC=C%10)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC%11=CC=C(C=C%11)O)C(N[C@@H](CC%12=CC=C(C=C%12)O)C(N[C@@H](CC%13=CC=CC=C%13)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@H](O)C)C(NCC(N[C@@H](CO)C(N[C@@H](CSSC[C@@H](C(N[C@@H](CCC(O)=O)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(N[C@H]%14[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O%14)=O)C(N[C@@H](CC%15=CC=CC=C%15)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC%16=CNC=N%16)C(N[C@H]9CC%17=CNC=N%17)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)NC%18=O)C(N[C@@H](CCCCN)C(N[C@@H](C)C(N[C@@H](CC%19=CC=CC=C%19)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC%20=CC=C(C=C%20)O)C(NCC(NC%18)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CN
• Molecular Weight: 7741.62
• References & Citations: [1]ZongYun Chen, et al. Hg1, novel peptide inhibitor specific for Kv1. 3 channels from first scorpion Kunitz-type potassium channel toxin family. Journal of biological chemistry 287.17 (2012): 13813-13821.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported