U-0521

• UNSPSC Description:

  U-0521 is the inhibitor of the catechol-O-methyltransferase (COMT). U-0521 has the potential for the research of Parkinson's disease[1].

• Target Antigen:

  COMT

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease;Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/u-0521.html

• Purity:

  98.67

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(C(C1=CC=C(C(O)=C1)O)=O)C

• Molecular Weight:

  180.20

• References & Citations:

  [1]Reches A, et al. Effect of 3',4'-dihydroxy-2-methyl-propriophenone (U-0521) on catechol-O-methyltransferase activity and on DOPA accumulation in rat red blood cells and corpus striatum. Biochem Pharmacol. 1982;31(21):3415-3418.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  5466-89-7