BMS-363131

• Description :

  BMS-363131 is a selective inhibitor for tryptase, with an IC50 [1].

• CAS Number :

  [384829-65-6]

• UNSPSC :

  12352005

• Target :

  Ser/Thr Protease

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Assay Protocol :

  https://www.medchemexpress.com/bms-363131.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(N1CCN(CC1)C(CCCCCC2=CC=CC=C2)=O)N3[C@@H]([C@H](C3=O)C[C@@H]4CN(CCC4)C(N)=N)C(O)=O

• Molecular Formula :

  C28H40N6O5

• Molecular Weight :

  540.65

• References & Citations :

  [1]Slusarchyk WA, et al., Synthesis of potent and highly selective inhibitors of human tryptase. Bioorg Med Chem Lett. 2002 Nov 4;12 (21) :3235-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported