JAK2-IN-10

JAK2-IN-10

• CAS Number: 3035735-18-0
• UNSPSC Description: JAK2-IN-10 (compound 5) is a potent JAK2 V617F inhibitor with an IC50 value of ≤10 nM[1].
• Target Antigen: JAK
• Type: Isotope-Labeled Compounds
• Related Pathways: Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt
• Applications: Cancer-Kinase/protease
• Field of Research: Cancer
• Smiles: O=C(N1C)N([C@@H]2CC[C@@](NC(C3CC3)=O)(C)CC2)C4=C1C=NC5=C4C(C6=CC(C=NN7C([2H])([2H])[2H])=C7C=C6)=C(C8=CN(CC)N=C8F)N5
• Molecular Weight: 612.71
• References & Citations: [1]Seoyoung Cho, et al. Tricyclic urea compounds as jak2 v617f inhibitors. WO2024086273A1. 2024.05.25.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported