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JAK2-IN-10

CAT: 0804-HY-161684-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-161684-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
JAK2-IN-10 (compound 5) is a potent JAK2 V617F inhibitor with an IC50 value of ≤10 nM[1].
CAS Number
3035735-18-0
UNSPSC
12352005
Target
JAK
Type
Isotope-Labeled Compounds
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
97.97
Smiles
O=C(N1C)N([C@@H]2CC[C@@](NC(C3CC3)=O)(C)CC2)C4=C1C=NC5=C4C(C6=CC(C=NN7C([2H])([2H])[2H])=C7C=C6)=C(C8=CN(CC)N=C8F)N5
Molecular Formula
C33H33D3FN9O2
Molecular Weight
612.71
References & Citations
[1]Seoyoung Cho, et al. Tricyclic urea compounds as jak2 v617f inhibitors. WO2024086273A1. 2024.05.25.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
JAK2

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T88297-01JAK2-IN-10
sc-390539JAK2 (C-10)
sc-390539 FITCJAK2 (C-10) FITC
sc-390539 PJAK2 (C-10) P
sc-390539 HRPJAK2 (C-10) HRP
sc-390539 ACJAK2 (C-10) AC
sc-390539 PEJAK2 (C-10) PE
sc-390539 BJAK2 (C-10) B
sc-390539 AF647JAK2 (C-10) Alexa Fluor® 647
sc-390539 AF594JAK2 (C-10) Alexa Fluor® 594

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