JAK2-IN-10

• UNSPSC Description:

  JAK2-IN-10 (compound 5) is a potent JAK2 V617F inhibitor with an IC50 value of ≤10 nM[1].

• Target Antigen:

  JAK

• Type:

  Isotope-Labeled Compounds

• Related Pathways:

  Epigenetics;JAK/STAT Signaling;Protein Tyrosine Kinase/RTK;Stem Cell/Wnt

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Smiles:

  O=C(N1C)N([C@@H]2CC[C@@](NC(C3CC3)=O)(C)CC2)C4=C1C=NC5=C4C(C6=CC(C=NN7C([2H])([2H])[2H])=C7C=C6)=C(C8=CN(CC)N=C8F)N5

• Molecular Weight:

  612.71

• References & Citations:

  [1]Seoyoung Cho, et al. Tricyclic urea compounds as jak2 v617f inhibitors. WO2024086273A1. 2024.05.25.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  3035735-18-0