JAK2-IN-10

• Target:

  JAK

• Related Pathways:

  Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Chromatin/Epigenetic|||Stem Cells|||Angiogenesis

• Bioactivity:

  JAK2-IN-10 (compound 5) is a potent inhibitor of JAK2v617f, with an IC50 value of ?10 nM.

• Smiles:

  O=C1N(C2=C3C(=C(N=C3NC=C2N1C)C4=CN(CC)N=C4F)C=5C=C6C(=CC5)N(C([2H])([2H])[2H])N=C6)[C@H]7CC[C@](NC(=O)C8CC8)(C)CC7

• Molecular Formula:

  C33H33D3FN9O2

• Molecular Weight:

  612.71

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3035735-18-0