BMS-983970

• Description :

  BMS-983970 is an oral pan-Notch inhibitor for the treatment of multiplecancers[1].

• UNSPSC :

  12352005

• Target :

  Notch

• Type :

  Reference compound

• Related Pathways :

  Neuronal Signaling; Stem Cell/Wnt

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/BMS-983970.html

• Concentration :

  10mM

• Purity :

  99.26

• Solubility :

  DMSO : ≥ 50 mg/mL

• Smiles :

  O=C(N[C@@H]1C(NC2=C(F)C=CC=C2C(C3=CC=CC=C3)=N1)=O)[C@H](CCC(F)(F)F)[C@H](CC4CC4)C(N)=O

• Molecular Formula :

  C26H26F4N4O3

• Molecular Weight :

  518.50

• References & Citations :

  [1]Ashvinikumar V. Gavai, et al. Abstract 1643: BMS-983970, an oral pan-Notch inhibitor for the treatment of cancer. Cancer Res October 1, 2014 74; 1643.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1584713-87-0]