Pomalidomide-C2-NH2

• Product Name Alternative:

  Cereblon Ligand-Linker Conjugates 15

• UNSPSC Description:

  Pomalidomide-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a PEG linker used in PROTAC technology.

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/e3-ligase-ligand-17.html

• Purity:

  99.32

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=O)CCC1N(C2=O)C(C3=C2C(NCCN)=CC=C3)=O

• Molecular Weight:

  316.31

• References & Citations:

  [1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Clinical Information:

  No Development Reported

• CAS Number:

  1957235-66-3