Pomalidomide-PEG5-C2-NH2 (hydrochloride)

• UNSPSC Description:

  Pomalidomide-PEG5-C2-NH2 hydrochloride is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.Pomalidomide-PEG5-C2-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTAC[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/pomalidomide-peg5-c2-nh2-hydrochloride.html

• Purity:

  98.94

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCOCCOCCOCCOCCOCCN)=CC=C3)=O)=O.Cl

• Molecular Weight:

  573.04

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported

• CAS Number:

  2357117-23-6