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Pomalidomide-C7-NH2

CAT: 0804-HY-155560Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-155560Size:1 Each
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Description
Pomalidomide-C7-NH2 (Pomalidomide 4'-alkylC7-amine) (Compound 24g) is an E3 Ligase Ligand-Linker Conjugates consisting of Pomalidomide and a linker. Pomalidomide-C7-NH2 can be used for synthesis of PROTACs[1].
CAS Number
2093387-55-2
Product Name Alternative
Pomalidomide 4'-alkylC7-amine
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-c7-nh2.html
Solubility
10 mM in DMSO
Smiles
O=C1NC(C(CC1)N2C(C3=C(C2=O)C(NCCCCCCCN)=CC=C3)=O)=O
Molecular Formula
C20H26N4O4
Molecular Weight
386.44
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Li Y, et al. Discovery of MD-224 as a First-in-Class, Highly Potent, and Efficacious Proteolysis Targeting Chimera Murine Double Minute 2 Degrader Capable of Achieving Complete and Durable Tumor Regression. J Med Chem. 2019 Jan 24;62 (2) :448-466.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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