Pomalidomide-PEG4-C2-NH2

• UNSPSC Description:

  Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/E3_Ligase_Ligand-Linker_Conjugates_22.html

• Purity:

  95.11

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCOCCN)=O

• Molecular Weight:

  492.52

• References & Citations:

  [1]Jian Jin, et al. Compositions and methods for treating ezh2-mediated cancer. WO2018081530A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  2225940-52-1