Pomalidomide-PEG3-C2-NH2 (hydrochloride)
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804-HY-128716B
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Pomalidomide-PEG3-C2-NH2 (hydrochloride)
- CAS Number: 2446474-09-3
- UNSPSC Description: Pomalidomide-PEG3-C2-NH2 (Cereblon Ligand-Linker Conjugates 5) hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and a linker used in PROTAC technology[1].
- Target Antigen: E3 Ligase Ligand-Linker Conjugates
- Type: Reference compound
- Related Pathways: PROTAC
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pomalidomide-peg3-c2-nh2-hydrochloride.html
- Purity: 95.36
- Solubility: 10 mM in DMSO
- Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC=C3NCCOCCOCCOCCN)=O.[H]Cl
- Molecular Weight: 484.93
- References & Citations: [1]Sato T, et al. Cereblon-Based Small-Molecule Compounds to Control Neural Stem Cell Proliferation in Regenerative Medicine. Front Cell Dev Biol. 2021;9:629326. Published 2021 Mar 11.|[2]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.
- Shipping Conditions: Blue Ice
- Storage Conditions: -20°C (Powder, sealed storage, away from moisture and light)
- Clinical Information: No Development Reported