Pomalidomide-5-C2-NH2 (hydrochloride)

• UNSPSC Description:

  Pomalidomide-5-C2-NH2 (hydrochloride) is a conjugate of E3 ligase ligand and linker, which can be used for PROTACs synthesis[1].

• Target Antigen:

  E3 Ligase Ligand-Linker Conjugates

• Type:

  Reference compound

• Related Pathways:

  PROTAC

• Applications:

  Cancer-programmed cell death

• Field of Research:

  cancer

• Assay Protocol:

  https://www.medchemexpress.com/pomalidomide-5-c2-nh2-hydrochloride.html

• Purity:

  99.17

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(NCCN)=C3)=O.[H]Cl

• Molecular Weight:

  352.77

• References & Citations:

  [1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture and light)

• Clinical Information:

  No Development Reported