Pomalidomide-5-C2-NH2 (hydrochloride)

Pomalidomide-5-C2-NH2 (hydrochloride)

• UNSPSC Description: Pomalidomide-5-C2-NH2 (hydrochloride) is a conjugate of E3 ligase ligand and linker, which can be used for PROTACs synthesis[1].
• Target Antigen: E3 Ligase Ligand-Linker Conjugates
• Type: Reference compound
• Related Pathways: PROTAC
• Applications: Cancer-programmed cell death
• Field of Research: cancer
• Assay Protocol: https://www.medchemexpress.com/pomalidomide-5-c2-nh2-hydrochloride.html
• Purity: 99.17
• Solubility: 10 mM in DMSO
• Smiles: O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(NCCN)=C3)=O.[H]Cl
• Molecular Weight: 352.77
• References & Citations: [1]Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.
• Shipping Conditions: Blue Ice
• Storage Conditions: -20°C (Powder, sealed storage, away from moisture and light)
• Clinical Information: No Development Reported