PD-1/PD-L1-IN-40
CAT:
804-HY-157811
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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PD-1/PD-L1-IN-40
- UNSPSC Description: PD-1/PD-L1-IN-40 (Compound EP16) is a PD-1/PD-L1 inhibitor. PD-1/PD-L1-IN-40 inhibits the generation of exosomal PD-L1 with IC50 = 0.108 μM. PD-1/PD-L1-IN-40 can serve as a leading compound for exosomal PD-L1 abrogation. PD-1/PD-L1-IN-40 can be used for the research of cancer[1].
- Target Antigen: PD-1/PD-L1
- Type: Reference compound
- Related Pathways: Immunology/Inflammation
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/pd-1-pd-l1-in-40.html
- Solubility: 10 mM in DMSO
- Smiles: O=C(C1=CC=C(C=C1)C2=CC3=C(NC=C3)N=C2)NCCN4CCOCC4
- Molecular Weight: 350.41
- References & Citations: [1]Sun JG, et al. Identification of the exosomal PD-L1 inhibitor to promote the PD-1 targeting therapy of gastric cancer. Eur J Med Chem. 2024 Feb 7;268:116182.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported