PD-L1/PD-1-IN-1

PD-L1/PD-1-IN-1

• CAS Number: 2753642-49-6
• UNSPSC Description: PD-L1/PD-1-IN-1 (compound 8j) is a potent inhibitor of PD-L1/PD interaction, with IC50 [1].
• Target Antigen: PD-1/PD-L1
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/pd-l1-pd-1-in-1.html
• Solubility: 10 mM in DMSO
• Smiles: ClC1=C(C2=CC=C(CNC(CO)(CO)CO)C(OC)=C2)C=CC=C1C3=CC=C4OCCOC4=C3
• Molecular Weight: 485.96
• References & Citations: [1]Damian Muszak, et al. Terphenyl-Based Small-Molecule Inhibitors of Programmed Cell Death-1/Programmed Death-Ligand 1 Protein–Protein Interaction. J Med Chem. 2021 Aug 12;64(15):11614-11636.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported