PD-1/PD-L1-IN-45

• UNSPSC Description:

  PD-1/PD-L1-IN-45 (Compound 2) is an inhibitor for PD-1/PD-L1 Interaction with EC50 of 21.8 nM[1].

• Target Antigen:

  PD-1/PD-L1

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/pd-1-pd-l1-in-45.html

• Smiles:

  CN(CCO)CC1=CN=C(C(NC2=CC=CC(C3=C(C)C(NC(C4=NC=C(CN[C@@H](C)CO)C=C4)=O)=CC=C3)=C2C)=O)C=C1

• Molecular Weight:

  596.72

• References & Citations:

  [1]Hec-Gałązka A, et al., Nonsymmetrically Substituted 1,1'-Biphenyl-Based Small Molecule Inhibitors of the PD-1/PD-L1 Interaction. ACS Med Chem Lett. 2024 Jun 3;15(6):828-836.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported