PD-1/PD-L1-IN 5

• CAS Number:

  2170209-51-3

• UNSPSC Description:

  PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1].

• Target Antigen:

  PD-1/PD-L1

• Type:

  Reference compound

• Related Pathways:

  Immunology/Inflammation

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cancer; Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/pd-1-pd-l1-in-5-1.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(C(S1)=NC2=C1CNCC2)NC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C#N

• Molecular Weight:

  418.47

• References & Citations:

  [1]Kaijiong Xiao, et al. Heterocyclic compounds as immunomodulators. WO2017222976A1.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported