PD-1/PD-L1-IN 5

PD-1/PD-L1-IN 5

• CAS Number: 2170209-51-3
• UNSPSC Description: PD-1/PD-L1-IN 5 is a PD-1/PD-L1 protein/protein interaction inhibitor extracted from patent WO2017222976A1, compound Example 1, has an IC50 of ≤100 nM[1].
• Target Antigen: PD-1/PD-L1
• Type: Reference compound
• Related Pathways: Immunology/Inflammation
• Applications: COVID-19-immunoregulation
• Field of Research: Cancer; Infection; Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/pd-1-pd-l1-in-5-1.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(C(S1)=NC2=C1CNCC2)NC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C#N
• Molecular Weight: 418.47
• References & Citations: [1]Kaijiong Xiao, et al. Heterocyclic compounds as immunomodulators. WO2017222976A1.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported