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BChE-IN-29

CAT: 0804-HY-162338Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-162338Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BChE-IN-29 (Compound 27a) is a BChE inhibitor (IC50: 0.078 μM and 0.74 μM for BChE and AChE respectively) . BChE-IN-29 has anti-inflammatory activity and can be used for research of AD[1].
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bche-in-29.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(C(N(CCC)CCC)=O)C=C1S(NCCN2CCCCCC2)(=O)=O
Molecular Formula
C22H37N3O3S
Molecular Weight
423.61
References & Citations
[1]Lu X, et al. Discovery, Structure-Based Modification, In Vitro, In Vivo, and In Silico Exploration of m-Sulfamoyl Benzoamide Derivatives as Selective Butyrylcholinesterase Inhibitors for Treating Alzheimer's Disease. ACS Chem Neurosci. 2024 Mar 7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE

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