JG-2016

• Description :

  JG-2016 is a potent inhibitor of histone acetyltransferase 1 (HAT1) with an IC50 of 14.8 μM. JG-2016 can inhibit the growth of multiple tumor cells and has anti-tumor activity[1].

• UNSPSC :

  12352005

• Target :

  Histone Acetyltransferase

• Type :

  Reference compound

• Related Pathways :

  Epigenetics

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/jg-2016.html

• Purity :

  98.44

• Solubility :

  DMSO : 100 mg/mL (ultrasonic)

• Smiles :

  O=C(N1)N=C2N(CCOCC(C)C)C3=CC(CC)=C(Cl)C=C3N=C2C1=O

• Molecular Formula :

  C18H21ClN4O3

• Molecular Weight :

  376.84

• References & Citations :

  [1]Joshua James GRUBER, et al. Modulators of histone acetyltransferase 1 and methods of treatment thereof. Patent, WO2022272313A1.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2887480-87-5]