JG-2016

• Description:

  JG-2016 is a potent inhibitor of histone acetyltransferase 1 (HAT1) with an IC50 of 14.8 μM. JG-2016 can inhibit the growth of multiple tumor cells and has anti-tumor activity[1].

• UNSPSC:

  12352005

• Target:

  Histone Acetyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/jg-2016.html

• Purity:

  98.44

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C (N1) N=C2N (CCOCC (C) C) C3=CC (CC) =C (Cl) C=C3N=C2C1=O

• Molecular Formula:

  C18H21ClN4O3

• Molecular Weight:

  376.84

• References & Citations:

  [1]Joshua James GRUBER, et al. Modulators of histone acetyltransferase 1 and methods of treatment thereof. Patent, WO2022272313A1.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2887480-87-5