JG-2016

• UNSPSC Description:

  JG-2016 is a potent inhibitor of histone acetyltransferase 1 (HAT1), with an IC50 of 14.8 μM in the HAT1 acetylation assays[1].

• Target Antigen:

  Histone Acetyltransferase

• Type:

  Reference compound

• Related Pathways:

  Epigenetics

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/jg-2016.html

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(N1)N=C2N(CCOCC(C)C)C3=CC(CC)=C(Cl)C=C3N=C2C1=O

• Molecular Weight:

  376.84

• References & Citations:

  [1]Joshua James GRUBER, et al. Modulators of histone acetyltransferase 1 and methods of treatment thereof. Patent, WO2022272313A1.

• Shipping Conditions:

  Room Temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2887480-87-5