DPI-2016

• Description :

  DPI-2016 is a antibacterial agent. DPI-2016 shows improved bactericidal activity (MIC, 0.25-8 μg/mL) against all bacterial strains compared to the aztreonam (HY-B0129) (MIC, 16->64 μg/mL) [1].

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/dpi-2016.html

• Solubility :

  10 mM in DMSO

• Smiles :

  OC([C@@H](O/N=C(C(N[C@H]1C(C)(C)N(OS(=O)(O)=O)C1=O)=O)/C2=C(SC(N)=N2)C)COC3=CC=C(C(N[C@@H]4CCNC4)=N)C=C3)=O

• Molecular Formula :

  C25H32N8O10S2

• Molecular Weight :

  668.70

• References & Citations :

  [1]Zhai L, et al. Improved synthesis and evaluation of preclinical pharmacodynamic parameters of a new monocyclic β-lactam DPI-2016. Bioorg Med Chem Lett. 2024 Jan 8:129615.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2760731-35-7]