JG-258

• UNSPSC Description:

  JG-258 is an inactive negative control for Hsp70 inhibitors[1].

• Target Antigen:

  HSP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/jg-258.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1/C(S/C(N1CC)=C\C2=[N+](C=CS2)CC3=CC=CC=C3)=C4N(CCS/4)C.[Cl-]

• Molecular Weight:

  452.06

• References & Citations:

  [1]Hao Shao, et al. Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70). J Med Chem. 2018 Jul 26;61(14):6163-6177.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  2241517-83-7