JG-258

• Description :

  JG-258 is an inactive negative control for Hsp70 inhibitors[1].

• UNSPSC :

  12352005

• Target :

  HSP

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/jg-258.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1/C(S/C(N1CC)=C\C2=[N+](C=CS2)CC3=CC=CC=C3)=C4N(CCS/4)C.[Cl-]

• Molecular Formula :

  C20H22ClN3OS3

• Molecular Weight :

  452.06

• References & Citations :

  [1]Hao Shao, et al. Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70) . J Med Chem. 2018 Jul 26;61 (14) :6163-6177.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2241517-83-7]