JG-258

• Description:

  JG-258 is an inactive negative control for Hsp70 inhibitors[1].

• UNSPSC:

  12352005

• Target:

  HSP

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage; Metabolic Enzyme/Protease

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/jg-258.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1/C (S/C (N1CC) =C\C2=[N+] (C=CS2) CC3=CC=CC=C3) =C4N (CCS/4) C.[Cl-]

• Molecular Formula:

  C20H22ClN3OS3

• Molecular Weight:

  452.06

• References & Citations:

  [1]Hao Shao, et al. Exploration of Benzothiazole Rhodacyanines as Allosteric Inhibitors of Protein-Protein Interactions with Heat Shock Protein 70 (Hsp70) . J Med Chem. 2018 Jul 26;61 (14) :6163-6177.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2241517-83-7