GT-2016

GT-2016

• CAS Number: 152241-24-2
• UNSPSC Description: GT-2016 is a potent, selective, and brain penetrant histamine H3 receptor antagonist with a Ki of 43.8 nM. GT-2016 displays selectivity against H1 and H2 receptors, and has non-active against histamine methyltransferase[1].
• Target Antigen: Histamine Receptor
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/gt-2016.html
• Solubility: 10 mM in DMSO
• Smiles: O=C(N1CCC(C2=CNC=N2)CC1)CCCCC3CCCCC3
• Molecular Weight: 317.47
• References & Citations: [1]C E Tedford, et al. Pharmacological characterization of GT-2016, a non-thiourea-containing histamine H3 receptor antagonist: in vitro and in vivo studies. J Pharmacol Exp Ther. 1995 Nov;275(2):598-604.
• Shipping Conditions: Room temperature
• Clinical Information: No Development Reported