Antituberculosis agent-10

• Description :

  Antituberculosis agent-10 (Compound 9) has excellent antibacterial activity against Mycobacterium tuberculosis (MIC = 0.3 μM) . Antituberculosis agent-10 inhibits protein synthesis by targeting the 50S ribosomal subunit of the bacterium, thus exerting its antibacterial effect. Antituberculosis agent-10 is orally active[1].

• UNSPSC :

  12352005

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antituberculosis-agent-10.html

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C1O[C@@H](CN)CN1C2=CC=C(C3=CC=C(S(=O)(C)=O)C=C3)C(F)=C2

• Molecular Formula :

  C17H17FN2O4S

• Molecular Weight :

  364.39

• References & Citations :

  [1]Boshoff HIM, et al. Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities. ACS Infect Dis. 2024 Apr 6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2095636-19-2]