Antituberculosis agent-10

• UNSPSC Description:

  Antituberculosis agent-10 (Compound 9) has excellent antibacterial activity against Mycobacterium tuberculosis (MIC = 0.3 μM). Antituberculosis agent-10 inhibits protein synthesis by targeting the 50S ribosomal subunit of the bacterium, thus exerting its antibacterial effect. Antituberculosis agent-10 is orally active[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antituberculosis-agent-10.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C1O[C@@H](CN)CN1C2=CC=C(C3=CC=C(S(=O)(C)=O)C=C3)C(F)=C2

• Molecular Weight:

  364.39

• References & Citations:

  [1]Boshoff HIM, et al. Mtb-Selective 5-Aminomethyl Oxazolidinone Prodrugs: Robust Potency and Potential Liabilities. ACS Infect Dis. 2024 Apr 6.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4