Antituberculosis agent-6

• UNSPSC Description:

  Antituberculosis agent-6 (compound 9g) is a potent antimycobacterial agent. Antituberculosis agent-6 shows significant activity against M. tuberculosis, with a MIC of 3.49 μM. Antituberculosis agent-6 also shows good antifungal activity against A. niger, with a MIC of 62.50 μM. Antituberculosis agent-6 shows high GI absorption[1].

• Target Antigen:

  Bacterial; Fungal

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/antituberculosis-agent-6.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CC1=NC2=C(C=CC=C2C=C1OC3=C(C(F)=CC=C3)C4(COC4)OCC5=CC=C(C=C5)C#N)F

• Molecular Weight:

  458.46

• References & Citations:

  [1]Shinde A, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3-(2-(3-(Substituted benzyloxy)oxetan-3-yl)-3-fluorophenoxy)-8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7(50):47096-47107.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  9007-83-4