Antituberculosis agent-6

• Description :

  Antituberculosis agent-6 (compound 9g) is a potent antimycobacterial agent. Antituberculosis agent-6 shows significant activity against M. tuberculosis, with a MIC of 3.49 μM. Antituberculosis agent-6 also shows good antifungal activity against A. niger, with a MIC of 62.50 μM. Antituberculosis agent-6 shows high GI absorption[1].

• UNSPSC :

  12352005

• Target :

  Bacterial; Fungal

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antituberculosis-agent-6.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CC1=NC2=C(C=CC=C2C=C1OC3=C(C(F)=CC=C3)C4(COC4)OCC5=CC=C(C=C5)C#N)F

• Molecular Formula :

  C27H20F2N2O3

• Molecular Weight :

  458.46

• References & Citations :

  [1]Shinde A, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3- (2- (3- (Substituted benzyloxy) oxetan-3-yl) -3-fluorophenoxy) -8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7 (50) :47096-47107.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2874263-72-4]