Antituberculosis agent-16

• Description :

  Antituberculosis agent-16 is an orally active antituberculosis agent. Antituberculosis agent-16 exhibits stable antituberculosis activity with a MIC of 0.48 μg/mL against Mycobacterium tuberculosis H37Rv sensitive strain and 0.49 μg/mL against multidrug-resistant strain 14862. Antituberculosis agent-16 shows high Caco-2 permeability. Antituberculosis agent-16 can be used for the research of infection[1].

• UNSPSC :

  12352005

• Target :

  Bacterial

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Smiles :

  O=C(C1=CC(C2=CC(OCCOC)=NC=C2)=CN1)N[C@H]3C4CC5C[C@@H](C4)C[C@H]3C5

• Molecular Formula :

  C23H29N3O3

• Molecular Weight :

  395.49

• References & Citations :

  [1]Wu Y, et al. Optimization of pyrrole-2-carboxamide to develop a potent antituberculosis agent with improved physicochemical property and druggability. Bioorg Chem. 2025 Oct;165:109016.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported