Antituberculosis agent-2

CAT: 0804-HY-146057Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-146057Size:1 Each
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Description
Antituberculosis agent-2 (Compound 8d) is an antituberculosis agent against agent-sensitive and multidrug-resistant tuberculosis. Antituberculosis agent-2 shows anti-tuberculosis activity with MIC values of 0.454, 1.757 and 1.644 μg/mL against M. tuberculosis H37Rv, 13946 and 14862, respectively. Antituberculosis agent-2 displays favorable mouse and human microsomal stability, low cytotoxicity, and acceptable oral bioavailability[1].
CAS Number
[2411741-01-8]
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antituberculosis-agent-2.html
Solubility
10 mM in DMSO
Smiles
O=C1C=C(C2=CC=C(O)C=C2)OC3=CC=C(O)C(CN4CCC4)=C13
Molecular Formula
C19H17NO4
Molecular Weight
323.34
References & Citations
[1]Zhao W, et al. Design, synthesis, and biological evaluation of novel 4H-chromen-4-one derivatives as antituberculosis agents against multidrug-resistant tuberculosis. Eur J Med Chem. 2020 Mar 1;189:112075.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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