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Antituberculosis agent-7

CAT: 0804-HY-152137Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-152137Size:1 Each
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Description
Antituberculosis agent-7, an oxetanyl-quinoline derivative, has shown good antibacterial activity against P. mirabilis with a MIC of 31.25 μM. Antituberculosis agent-7 shows good antifungal activity against A. niger with a MIC of 62.5 μM. Antituberculosis agent-7 shows excellent antimycobacterial activity with MIC 3.41 μM for M. tuberculosis H37Rv[1].
CAS Number
[2874263-73-5]
UNSPSC
12352005
Target
Antibiotic; Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/antituberculosis-agent-7.html
Solubility
10 mM in DMSO
Smiles
CC1=NC2=C(C=CC=C2C=C1OC3=C(C(F)=CC=C3)C4(COC4)OCC5=CC(F)=CC(F)=C5)F
Molecular Formula
C26H19F4NO3
Molecular Weight
469.43
References & Citations
[1]Abhijit Shinde, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3- (2- (3- (Substituted benzyloxy) oxetan-3-yl) -3-fluorophenoxy) -8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7 (50) :47096-47107.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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