Products for Research Use Only
RegisterLogin

Antituberculosis agent-7

CAT: 0804-HY-152137Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-152137Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Antituberculosis agent-7, an oxetanyl-quinoline derivative, has shown good antibacterial activity against P. mirabilis with a MIC of 31.25 μM. Antituberculosis agent-7 shows good antifungal activity against A. niger with a MIC of 62.5 μM. Antituberculosis agent-7 shows excellent antimycobacterial activity with MIC 3.41 μM for M. tuberculosis H37Rv[1].
CAS Number
2874263-73-5
UNSPSC
12352005
Target
Antibiotic; Bacterial; Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/antituberculosis-agent-7.html
Solubility
10 mM in DMSO
Smiles
CC1=NC2=C(C=CC=C2C=C1OC3=C(C(F)=CC=C3)C4(COC4)OCC5=CC(F)=CC(F)=C5)F
Molecular Formula
C26H19F4NO3
Molecular Weight
469.43
References & Citations
[1]Abhijit Shinde, et al. Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3- (2- (3- (Substituted benzyloxy) oxetan-3-yl) -3-fluorophenoxy) -8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. ACS Omega. 2022 Dec 6;7 (50) :47096-47107.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

Antituberculosis agent-7
CAS Number2874263-73-5
PubChem CID166642472
IUPAC Name3-[2-[3-[(3,5-difluorophenyl)methoxy]oxetan-3-yl]-3-fluorophenoxy]-8-fluoro-2-methylquinoline
Molecular FormulaC26H19F4NO3
Molecular Weight469.4
XLogP5.1
Topological Polar Surface Area40.6
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Heavy Atom Count34
Formal Charge0
Complexity672
SMILES
CC1=C(C=C2C=CC=C(C2=N1)F)OC3=C(C(=CC=C3)F)C4(COC4)OCC5=CC(=CC(=C5)F)F
InChI
InChI=1S/C26H19F4NO3/c1-15-23(10-17-4-2-6-21(30)25(17)31-15)34-22-7-3-5-20(29)24(22)26(13-32-14-26)33-12-16-8-18(27)11-19(28)9-16/h2-11H,12-14H2,1H3
InChIKey
YLGFHYCMWZAAJE-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Antituberculosis agent-7
CAS: 2874263-73-5
CID: 166642472
Formula: C26H19F4NO3
MW: 469.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight469.4
XLogP35.1
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count8
Rotatable Bond Count6
Exact Mass469.13010612
Monoisotopic Mass469.13010612
Topological Polar Surface Area40.6 Ų
Heavy Atom Count34
Formal Charge0
Complexity672
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-151205Antituberculosis agent-3
HY-152138Antituberculosis agent-8
HY-152136Antituberculosis agent-6
HY-149064Antituberculosis agent-9
HY-163486Antituberculosis agent-10
HY-178436Antituberculosis agent-16
HY-175183Antituberculosis agent-15
HY-168860Antituberculosis agent-13
HY-146057Antituberculosis agent-2
HY-146055Antituberculosis agent-1

Alternative Products

CatalogName
T75019-01Antituberculosis agent-7
T74769-01Antituberculosis agent-9
MBS5803597Antituberculosis agent-2
GTR19212903-01Antituberculosis agent-6
GTR19263786-01Antituberculosis agent-15
T200663-01Antituberculosis agent-12
MBS5803928Antituberculosis agent-1
GTR19250487-01Antituberculosis agent-13
GTR19212901-01Antituberculosis agent-8
T63286-01Antituberculosis agent-3

Popular Products