Antituberculosis agent-5

• Description :

  Antituberculosis agent-5 (compound 52) is a nitrofuranylamide derivative, inhibits M. tuberculosis UDP-Gal mutase. Antituberculosis agent-5 inhibits Glf activity with an IC50 value of 99 μM/mL and resists tuberculosis (TB) with a MIC value of 1.6 μg/mL[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319

• Target :

  Bacterial

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/antituberculosis-agent-5.html

• Purity :

  99.76

• Solubility :

  DMSO : 100 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  O=C(C1=CC=C([N+]([O-])=O)O1)NCC2=CC=CC=C2OC

• Molecular Formula :

  C13H12N2O5

• Molecular Weight :

  276.24

• Precautions :

  H315, H319

• References & Citations :

  [1]Tangallapally RP, et al. Synthesis and evaluation of nitrofuranylamides as novel antituberculosis agents. J Med Chem. 2004 Oct 7;47 (21) :5276-83.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [313981-44-1]