BRD-7880

• Description :

  BRD-7880 is a potent and highly specific inhibitor of Aurora Kinase B (AURKB) and Aurora Kinase C (AURKC), with IC50 values of 7 nM and 12 nM, respectively[1].

• UNSPSC :

  12352005

• Target :

  Aurora Kinase

• Type :

  Reference compound

• Related Pathways :

  Cell Cycle/DNA Damage; Epigenetics

• Applications :

  Cancer-Kinase/protease

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/brd-7880.html

• Smiles :

  O=C1C2=CC(NC(NC3=CC=C(C=C3)OC)=O)=CC=C2O[C@H]([C@H](CN1[C@@H](C)CO)C)CN(C)CC4=CC=C(OCO5)C5=C4

• Molecular Formula :

  C32H38N4O7

• Molecular Weight :

  590.67

• References & Citations :

  [1]Yu C, et al. High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines[J]. Nature biotechnology, 2016, 34 (4) : 419-423.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• Isoform :

  Aurora A; Aurora B; Aurora C

• CAS Number :

  [1456542-69-0]