BRD-7880

CAT: 0804-HY-123610Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-123610Size:1 Each
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Description
BRD-7880 is a potent and highly specific inhibitor of Aurora Kinase B (AURKB) and Aurora Kinase C (AURKC), with IC50 values of 7 nM and 12 nM, respectively[1].
CAS Number
[1456542-69-0]
UNSPSC
12352005
Target
Aurora Kinase
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/brd-7880.html
Smiles
O=C1C2=CC(NC(NC3=CC=C(C=C3)OC)=O)=CC=C2O[C@H]([C@H](CN1[C@@H](C)CO)C)CN(C)CC4=CC=C(OCO5)C5=C4
Molecular Formula
C32H38N4O7
Molecular Weight
590.67
References & Citations
[1]Yu C, et al. High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines[J]. Nature biotechnology, 2016, 34 (4) : 419-423.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Aurora A; Aurora B; Aurora C

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