BRD-7880

• UNSPSC Description:

  BRD-7880 is a potent and highly specific inhibitor of Aurora Kinase B (AURKB) and Aurora Kinase C (AURKC), with IC50 values of 7 nM and 12 nM, respectively[1].

• Target Antigen:

  Aurora Kinase

• Type:

  Reference compound

• Related Pathways:

  Cell Cycle/DNA Damage;Epigenetics

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/brd-7880.html

• Smiles:

  O=C1C2=CC(NC(NC3=CC=C(C=C3)OC)=O)=CC=C2O[C@H]([C@H](CN1[C@@H](C)CO)C)CN(C)CC4=CC=C(OCO5)C5=C4

• Molecular Weight:

  590.67

• References & Citations:

  [1]Yu C, et al. High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines[J]. Nature biotechnology, 2016, 34(4): 419-423.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  1456542-69-0