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BRD-4592

CAT: 0804-HY-122016ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-122016ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BRD-4592 is an allosteric inhibitor targeting Mycobacterium tuberculosis tryptophan synthase (TrpAB) . BRD-4592 binds at the α-β-subunit interface of TrpAB, with an IC50 of 70.9 nM for the α-subunit and 22.6 nM for the β-subunit[1].
CAS Number
2119598-24-0
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Smiles
N#C[C@H]1[C@H](C2=CC=C(C3=C(C=CC=C3)F)C=C2)[C@@H](N1)CO
Molecular Formula
C17H15FN2O
Molecular Weight
282.31
References & Citations
[1]Samantha Wellington, et al. A small-molecule allosteric inhibitor of Mycobacterium tuberculosis tryptophan synthase. Nat Chem Biol. 2017 Sep;13 (9) :943-950.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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