BRD-K44839765

• UNSPSC Description:

  BRD-K44839765 is selective against Bcl-2 with an IC50 value of 5.6 μM in IMR-90 cell. BRD-K44839765 has oral activity[1].

• Target Antigen:

  Bcl-2 Family

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/brd-k44839765.html

• Smiles:

  CC1=CC=CC=C1C(NC2=CC3=C(N=C(S3)SCC(NC4=CC=CC=C4)=O)C=C2)=O

• Molecular Weight:

  433.55

• References & Citations:

  [1]Felix Wong, et al. Discovering small-molecule senolytics with deep neural networks. Nat Aging. 2023 Jun;3(6):734-750.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  303066-86-6