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BChE-IN-10

CAT: 0804-HY-N10486Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-N10486Size:1 Each
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Description
BChE-IN-10 (compound 6) is a potent butyrylcholinesterase (BChE) mixed-type inhibitor with an IC50 value of 6.4 μM. BChE-IN-10 can be isolated from Bletilla striata. BChE-IN-10 can be used for the research of Alzheimer's disease (AD) [1].
CAS Number
2185837-61-8
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bche-in-10.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(CC2=C(C=CC3=C(C(OC)=CC=C34)O)C4=C(C=C2O)OC)C=C1
Molecular Formula
C23H20O5
Molecular Weight
376.40
References & Citations
[1]Liu Y, et al. Biological evaluation, molecular modeling and dynamics simulation of phenanthrenes isolated from Bletilla striata as butyrylcholinesterase inhibitors. Sci Rep. 2022 Aug 11;12 (1) :13649.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
BChE

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